It's a test that measures the amount of lactic acid (also called "lactate") in your blood. This acid is made in muscle cells and red blood cells. It forms when your body turns food into Lactic acid, also called lactate, is a product of pyruvate metabolism under anaerobic conditions. The tissues that produce most lactic acid are the muscle cells and red blood cells. An elevated lactate level and a pH equal to or less than 7.35 cause lactic acidosis. Lactate is one of the substances produced by cells as the body turns food into energy (cell metabolism), with the highest level of production occurring in the muscles. Depending on pH, it is sometimes present in the form of lactic acid. The levels of blood lactate and fibrinogen may represent the severity of children with traumatic brain injury and may be risk factors for poor prognosis of children with traumatic brain injury. Traumatic brain injury (TBI) is a significant cause of morbidity and mortality in pediatric patients, leading to long-term physical, cognitive, and Blood lactate concentration ([La −] b) is one of the most often measured parameters during clinical exercise testing as well as during performance testing of athletes.While an elevated [La −] b may be indicative of ischemia or hypoxemia, it may also be a "normal" physiological response to exertion. In response to "all-out" maximal exertion lasting 30-120 seconds, peak [La −] b Overview What is lactic acidosis? Lactic acidosis is a buildup of lactic acid in your bloodstream. It happens when your body produces too much lactic acid and/or can't metabolize enough of the lactic acid it produces. Your liver and kidneys normally clear excess lactic acid from your body. Cite Share Subject Physiology - Other Issue Section: Articles Key points Blood lactate concentrations reflect the balance between lactate production and clearance. Glycolysis, gluconeogenesis and pyruvate conversion to and from lactate are linked with NAD + and NADH. Lactate is the end product of anaerobic metabolism. Lactate is generated mainly in skeletal muscle, brain, erythrocytes, the skin and the gut and is disposed of by gluconeogenesis in the liver and by complete oxidation. Lactic acidosis can be due to excessive lactate formation or decreased removal. Blood lactate levels are elevated in diseases affecting energy metabolism. Lactate is an intermediate product produced in the breakdown of glucose. Its elevation reflects either overuse of the system or a direct block (such as block by pyruvate dehydrogenase or pyruvate carboxylase). Disorders in mitochondrial energy metabolism or fatty acid Lactic acid is mainly produced in muscle cells and red blood cells. It forms when the body breaks down carbohydrates to use for energy when oxygen levels are low. Times when your body's oxygen level might drop include: A test can be done to measure the amount of lactic acid in the blood. GvEe.